The game will be played at the Baba Yara Stadium with the game set to be shown live on television on the StarTimes Adepa TV channel, starting at 3:00pm local time.
Asante Kotoko will be playing their first game of the campaign after sitting out their opening two matches due to their campaign in Africa, whilst Hearts of Oak will go into their third game of this season, looking for their first win.
Another game to look out for this afternoon, is at the NAB I Park, Dormaa-Ahenkro where local side Aduana FC will welcome FC Samartex with both sides unbeaten in the campaign after two matches.
Gold Stars, who have lost their opening two matches, will look for their first point(s) of the campaign as they host Bechem United at the Dun's Park, Bibiani.
Kotoku Royals will look for their second win of the competition as they host fellow promoted side Nsoatreman FC at the Cape Coast Stadium.
Real Tamale United, (RTU), will be home to Legon Cities at the Aliu Mahama Sports Stadium in Tamale as they look for their first win of the campaign.
Karela United will hope to make their home advantage count when they welcome Dreams FC to the Crossby Awuah Memorial (CAM) Park at Anyinase.
The Matchday Three fixtures will close with a game on Monday at the NAB I Park, Dormaa-Ahenkro where Berekum Chelsea will host Medeama SC in what should be a tough duel for both sides.
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