1. ATHLETIC MADRID VS GRANADA
Following their exit from the Champions League, Atletico Madrid will try to reinforce their role in the top four of the La Liga table on Wednesday, when they host Granada.
Los Colchoneros earned a victory over Espanyol in dramatic way on Sunday, moving within three points of fifth place with six games to play as a result.
2. OSASUNA VS REAL MADRID
Real Madrid will appear to take another step towards La Liga identity on Wednesday, when they take on Osasuna at the Estadio El Sadar.
Los Blancos pulled off a flashy turn to defeat Sevilla at the weekend, leaving them wanting 10 points from their last six games to secure the trophy.
3. BREST VS LYON
Lyon will try to extend their unbeaten league run to five matches when they travel to the Stade Francis-Le Ble to take on Brest on Wednesday.
The hosts, by contrast, have struggled for wins before, and surely one of their last five clubs ended in victory.
4. MARSEILLE VS NANTES
Looking to bounce back from a 2-1 loss to Paris-Saint Germain in Le Classique, Marseille could be looking to tighten their control in the second area with a win against Nantes on Wednesday.
The visitors, on the other hand, can extend their unbeaten run to four clubs with a winning final result at the Stade Velodrome.
5. MONACO VS NICE
Monaco and Nice will meet at the Stade Louis II on Wednesday night knowing victory will bring either side closer to European football revenue next season.
As it stands, fourth-placed Nice retain a one-point lead over their sixth-placed opponents in the Ligue 1 standings, with both clubs still in contention for second place after Marseille loss at Paris Saint-Germain over the weekend.
6. CHELSEA VS ARSENAL
Coming off the back of contrasting fortunes in their weekend clashes, Chelsea and Arsenal teamed up for battle in Wednesday's London Premier League derby at Stamford Bridge.
The Blues beat Crystal Palace 2-0 in their FA Cup semi-final over the weekend, while Mikel Arteta's side slumped to a third defeat at the top during their trip to Southampton.
7. EVERTON VS LEICESTER CITY
Having enjoyed the rare luxury of a weekend off, Everton continue their fight for Premier League survival against Leicester City at Goodison Park on Wednesday night.
The Toffees increased their chances of survival with a 1-0 win over Manchester United last time out, even as Brendan Rodgers' side lost 2-1 to Newcastle United.
8. NEWCASTLE UNITED VS CRYSTAL PALACE
Newcastle United will play host to Crystal Palace on Wednesday night knowing victory will end any lingering fears about a staggering relegation from the Premier League.
However, the Magpies could also be closer to the top 10 of the standings, especially with Palace, in 13th place, only sitting above them on difference of intentions.
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