Peptic ulcer may be duodenal or gastric. Duodenal ulcers are more often in younger adults. Gastric ulcers usually occur after middle age. Gastric ulcers should be taken seriously because they may be malignant. Peptic ulcers may lead to life threatening complications of bleeding, perforation and gastric outlet obstruction.
Let's see some of the causes of peptic ulcer disease.
Helicobacter pylori ( H. Pylori) infection
Excessive secretion of gastric acid
Inadequate protection of the lining of the stomach and duodenum against digestion by acid and pepsin.
Medicines e.g. non-steroidal anti-inflammatory drugs (NSAIDs), corticosteroids.
What are the symptoms of peptic ulcers; Episodic abdominal pain ( often aggravated by dietary indiscretions and lifestyle)
May be a minor discomfort, gnawing, burning, dull ache or very severe pain
Typically pain is in the epigastric or right hypochondriac
Occasionally high up behind the sternum or low down around the umbilicus. Etc.
There may be no abdominal signs
Weight loss ( sometimes in gastric ulcer )
Weight gain ( sometimes in duodenal ulcer )
Tenderness - epigastrium, right hypochondriac or umbilical region.
Magnesium trisilicate, oral, 15ml 8 hourly ( in - between meals and at bedtime to control dyspepsia) OR Aluminium hydroxide, oral, 500mg 6hourly ( in - between meals and bedtime).
2nd line treatment: Omeprazole, oral, 20mg daily for 4 weeks. Repeat cause if ulcer is not fully healed.
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