The Switzerland international was sent off in the first half for a challenge on Joao Cancelo, with Arsenal behind 2-0.
Granit Xhaka was sent off in the first half against Manchester City, making Arsenal's day at the Etihad Stadium even worse.
When Xhaka was sent out 10 minutes before halftime, the Gunners were already down 2-0 to the Premier League champions.
Arsenal's season is shaping up to be a difficult one, with Mikel Arteta's team having lost their first two games.
City had already taken command thanks to goals from Ilkay Gundogan and Ferran Torres when Xhaka surged in with a two-footed challenge on Joao Cancelo.
Xhaka received a straight red card, making it his fourth dismissal in the Premier League since the start of the 2016-17 season.
The match ended in a thrashing 5-0 win for Pep Guardiola's side, with Arsenal yet to get a single goal in the league campaign.
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